ADE is a set of two ciliated neurons with endings in the deirid
sensilla, which are situated
in the alae on the lateral lines. The cell bodies of ADE are part of
a small group of cells situated
laterally behind the second bulb of the pharynx. Processes enter the
retro-vesicular ganglion
via the deirid commissures and then run anteriorly in the ventral
ganglion (e). Here they cross
over to the contralateral side and run posteriorly for a short
distance before ending. Most of
the synaptic output is situated in this region and is predominantly
to RIG (a) and RIG in
association with AVA (b) although there is usually a bias towards RIG
in these dyadic
synapses. The process to the ciliated ending has a branch, which
enters the ring neuropile
laterally, running anteriorly through the ring neuropile and making
some rather small synapses
to diverse partners; OLL, RMD (c), CEP and FLP are the most prominent
synaptic partners
in this region. ADE receives some synaptic input from BDU (*b), FLP
(*c), AVM (*) and
IL2L/IL2R. It has gap junctions to AVK (d) in the neuropile of the
ventral ganglion. ADE
neurons have been shown to contain dopamine (Sulston et al.
1975).
Magnifications: (a, c, d) x 25500, (b) x 12750.
Web adaptation, Thomas Boulin,
for Wormatlas, 2001, 2002