Type: Interneuron
Connectivity:
- In MoW: PVP
- In WormWiring: PVPL_h, PVPR_h
- In Nemanode: PVP
In Wormbase: PVP, PVPL, PVPR
Lineage: AB plppppaaa, AB prppppaaa
Location: Pre-anal ganglion
Description: Interneuron. Differences in connectivity observed between hermaphrodites and males. In hermaphrodites PVP neurites were observed to make branches around the vulva suggesting they may form synapses with egg-laying muscles (Hobert and Hall, 1999). The PVPL/PVPR processes cross over in the pre-anal ganglion and then grow forward on the opposite side of the cord to the nerve ring. The PVPL process invariably crosses in front of the PVPR process. PVPL and PVPR somas are nearly opposite one another in the embryo and early larval stages. However, in the adult, this symmetry and order is lost and cells are situated almost linearly within PAG (Durbin, 1987).

Neurotransmitter/ Neuropeptide:
- Acetylcholine
(Duerr et al., 2008)
Innexin expression:
- INX-1a
- INX-3
- INX-7
- INX-10
- INX-14
- INX-18a
- UNC-7
- UNC-9
(Bhattacharya et al., 2019; Altun et al., 2009)
Receptor expression:
Function:
- PVPR pioneers the left tract of the ventral cord and this function appears to be a joint action of PVPR and PVQL processes; PVQ axons pioneer the lumber commissures and continue to travel alongside the PVP processes in the VNC (Durbin, 1987; Wadsworth and Hedgecock, 1996; Wadsworth et al., 1996). When PVPR precursor is ablated in the embryo, PVQL and AVKR growth cones migrate towards the right side (Durbin, 1987; Antebi et al., 1997).
Reporters:
- At CGC:
- Other: