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CONNECTIVITY:
MOW
Sulston et al., 1980

IN WB

CELL ID:

   
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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

PVT

Interneuron

ABplpappppa

Preanal ganglion

Unknown

None
DESCRIPTION

Interneuron, projects along ventral cord to ring. Hermaphrodites and males exhibit some differences in PVT connectivity.

Functions: Midline neuroblast, secretes UNC-6, serves as a guidepost neuron to guide growing axons from the lumbar ganglia in the posteriormost region of the ventral cord. When PVT is ablated embryonically, these axons follow multiple routes to enter the ventral cord instead of making tight bundles (A. Antebi et al, 1997) (Ren X-C. et al., 1999). Postembryonically, PVT functions to keep the ventral cord fascicles intact. Early larval ablation of PVT induces axons of AVKL/R, PVQL/R, HSNL/R and RMEV to aberrantly cross the ventral midline (Aurelio O. et al, 2002).

Receptor expression: Expresses a splice variant of the tyramine receptor SER-2 (variable expression) (Tsalik E. L. et al, 2003). Expresses the serotonin receptor SER-4 (variable expression) (Tsalik E. L. et al, 2003).




 

 

 



Male Wiring Project

For Male Wiring Project details see "Connectivity" link in Emmons lab website.