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|Putative mechanosensory neuron||QL ap
||Left lumbar ganglion||Unknown||PHso2L||DESCRIPTION|
Single neuron with basal body. It is directly exposed to the pseudocoelomic body fluid. An anterior process projects into preanal gangion and usually ends just posterior to the vulva, although can be slightly shorter or longer. Posterior process is ensheathed by PHso2L cell. Postembryonically born.
See a 3-D reconstruction of PQR by R. Newbury & Moerman lab. (Cell labels are shown below. 3-Dmovie was created from confocal images of a strain expressing the GFP marker linked to the promoter for ZC53.7 using Zeiss LSM 5 Pascal software v. 3.2). See also Phamid image gallery.
Functions: Along with AQR, URX and AUA, PQR regulate social feeding (or aggregation on a bacterial lawn) and bordering (the accumulation of animals on the thickest part of a bacterial lawn) behavior since suppressing the activity of AQR, PQR, URX neurons inhibits social feeding (Coates J. C. and de Bono M., 2002). AQR, PQR and URX function as sensors of environmental oxygen which is a quantitative regulator of social feeding (Gray J. M. et al, 2004). Decreases in oxygen leads to a dose-dependent suppression of social feeding behavior and bordering. Oxygen acts in parallel to NPR-1 in regulating social feeding behavior.
Receptor expression: Expresses orphan receptor (chemosensory/odorant?) guanylyl cyclase, GCY-32 (Yu S. et al, 1997). Express neuropeptide Y receptor like protein, NPR-1 which mediates social feeding behavior (Coates J. C. and de Bono M., 2002). Express specific soluble guanylate cyclase homologue, GCY-35 which binds molecular oxygen and mediates oxygen sensation (Gray J. M. et al, 2004).
See gcy-32::GFP expression in PQR (Yu S. et al, 1997)