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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

DVA

Interneuron

AB.prppppapp Dorsorectal ganglion

Not known

None
DESCRIPTION

Ring interneurons.

Functions: Mechanosensory integration. The PVD and DVA neurons are presynaptic to both the forward and backing interneurons, and provide input to both the anterior and posterior touch circuits. Animals lacking these neurons respond to tap stimulus with diminished forward accelerations and reversals. These neurons, therefore, seem to maintain the overall activity of the touch circuit (Driscoll M., Kaplan J., 1997)( Wicks S. R. et al, 1996)

Receptor expression: Expresses glutamate receptor subunits, GLR-4, GLR-5 and NMR-1(Brockie P.J. et al 2001). Expresses a splice variant of the tyramine receptor SER-2 (Tsalik E. L. et al, 2003). Variably expresses the serotonin receptor SER-4 (can be instead DVC neuron) (Tsalik E. L. et al, 2003). Suggested to express GABA-A/glycine receptor-like protein GGR-3 (Fujiwara et al, 1996).




See glr-4-GFP expression in DVA (Brockie P.J. et al 2001).