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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

CEPDL
CEPDR
CEPVL
CEPVR

Sensory neuron

(putative Mechanosensory)

ABplaaaaappa
ABarpapaappa
ABplpaappppa
ABprpaappppa

Head

Dopamine.

(express TH, CAT-2. Lints R. and Emmons S.W. 1999)

CEPshDL

CEPshDR

CEPsh VL

CEPsh VR
and
CEPsoDL

CEPso DR

CEPsoVL

CEPsoVR

DESCRIPTION

Neurons of cephalic sensilla, the CEP sensory processes extend to the tip of the nose. Express acetylcholinesterase of class A, ACE-1 (Culetto et al 1999). CEP neurons are directly exposed to the pseudocoelomic body fluid.

See Cephalic image gallery.

Functions: Mechanosensory function in the head. When well-fed C. elegans hermaphrodites are washed clean of bacteria and then reintroduced to the bacterial lawn, they move more slowly than when transferred to an environment without bacteria. This behavior is described as "basal slowing response". The three classes of dopaminergic neurons (CEPs, ADEs, and PDEs) function redundantly to sense the mechanosensory stimulus from bacteria and mediate the motor circuit to control this behavioral change (Sawin E. R. et al, 2000).

Receptor expression: Express the dopamine receptor DOP-2 (Suo S. et al, 2003 ).