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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

AVEL
AVER

Interneuron AB alpppaaaa
AB praaaaaaa
Lateral ganglia of head

Express FMRFamide-like peptide, FLP-1 precursor (Nelson L.S. et al 1998).

None
DESCRIPTION

Ventral cord interneurons. AVE's have the same postsynaptic targets as AVD's, but processes of AVE's are restricted to anterior cord, ending shortly before vulva.

Functions: Command interneuron. Drive backward movement of the animal along with AVA, AVD and A-type motor neurons. See Locomotory circuit.

Receptor expression: Express glutamate receptor subunits, GLR-1 , GLR-2, GLR-5, NMR-1 and NMR-2 (Maricq A. V. et al 1995)(Brockie P.J. et al 2001).









See Quicktime movie of confocal stack opt-3::GFP expression in AVEL, AVER ( by Christina Gleason/Miller lab)

(Fei, Y. J. et al. (2000) A novel H(+)-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H(+) channel and an exclusive expression in neurons, J Biol Chem 275, 9563-71.). (Note that neurons shown as AVA's in this publication are actually AVE's. D. Miller, pers. comm.).