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|Body, Ventral cord.||
Serotonin (only VC4
ACh (C. elegans book II CSHL Press, 1997.Rand J.B. and Nonet M.L. Appendix II) (express ChAT and VAChT (Duerr J. S. et al, 2001; Lickteig K. M et al, 2001))
Hermaphrodite specific ventral
cord motor neurons. The neurons are born in L1, and begin to send out processes in late L3. These processes branch in the region of the vulva during L4. VC4 and VC5 have short ventral cord processes, but send branched processes dorsally along the vulval hypodermis on each side of the vulval slit. VC1-3 and VC6 send less branched processes to vulval regions but have longer processes in the ventral cord (in R side fascicle). The dorsal branches of VC axons innervate vm2 vulval muscles. These neurons, except VC4 and VC5, also innervate ventral body muscles.
Functions: Acetylcholine released from the VC neurons inhibits egg-laying behavior . This may be caused by inhibition of presynaptic neurotransmitter release by HSN neurons following the activation of the G-protein- coupled acetylcholine receptor 2 (GAR-2) signaling (Bany I. A. et al, 2003). VC4 and VC5 can also induce the active phase of egg-laying by releasing serotonin (Waggoner L. E. et al, 1998).