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CONNECTIVITY:
MOW
Sulston et al., 1980

IN WB [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11]

CELL ID << PREVIOUS NEXT >>

CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

AS1
AS2
AS3
AS4
AS5
AS6
AS7
AS8
AS9
AS10
AS11

Motor neuron P1 apa
P2 apa
P3 apa
P4 apa
P5 apa
P6 apa
P7 apa
P8 apa
P9 apa
P10 apa
P11 apa
Body; VC

ACh

(C. elegans book II CSHL Press, 1997.Rand J.B. and Nonet M.L. Appendix II: Neurotransmitter assignments for specific neurons)

None
DESCRIPTION

Ventral cord motor neurons, born postembryonically. Innervate dorsal muscles, no ventral counterpart, similar to VAn but receive additional synaptic input from AVB. Note that unlike AS1-10, the commissure of AS11 originates from the posterior process. All AS commissures to DC run from the right side of the body. Hermaphrodites and males exhibit some differences in ASn connectivity.

Receptor expression: Unknown.





Male Wiring Project

Note: In males, the AS11 cell body lies posterior to the male-specific CP9 neuron, which defines the anterior boundary of the male pre-anal ganglion (see Male Tail Cell ID). In males, AS11 is therefore considered part of the pre-anal ganglion rather than the ventral nerve cord.

For Male Wiring Project details see "Connectivity" link in Emmons lab website.


Schematic Diagrams of Ventral Cord motor neurons:

AS neurons DA and DB neurons VA neurons
VB neurons VC neurons DD and VD neurons

In all diagrams,axon processes with neuromuscular synapses (NMJ) are shown as whereas dendritic processes where synaptic inputs are received are shown as .

Class A axons run forward in both cords (VNC and DC) whereas the class B axons run backwards. The dendritic branches of the dorsal and ventral class A neurons run in opposite directions as do those from class Bneurons. Ventral class D neurons receive their synaptic input on the dorsal side and give NMJ's on the ventral side. The dorsal type D neurons have half the periodicity of their ventral counterparts and receive synapses on the ventral side and give NMJ's on the dorsal side. Class AS neurons only synapse on the dorsal side and have no ventral counterpart, whereas, the class C neurons only synapse on the ventral side. The synapses from class C motor neurons onto body muscles are less dense than for the other classes (White J. et al, 1976)