STUDIES ON THE DEVELOPMENT AND ORGANISATION OF THE
NERVOUS SYSTEM OF CAENORHABDITIS ELEGANS
Richard Michael Durbin
A dissertation submitted to the University of
Cambridge for examination for the degree of
Doctor of Philosophy
April, 1987 Kings College
The work described in this dissertation was carried out between January 1984 and March 1987 at the MRC Laboratory of Molecular Biology, Cambridge. As described in the summary, two different approaches were used in this work, and the main body of the dissertation is split into two parts, each with its own introduction. However the introduction to the first part provides much of the general background. There is a final conclusion which considers both parts in a broader setting.
It is customary to list a long series of acknowledgements somewhere in the preface to a dissertation. I have derived enormous personal and scientific benefit from my time spent at the Laboratory of Molecular Biology, both from the people who work here and the environment that they have created. I am only going to thank personally two people, my supervisor John White, to whom I owe so much that it would be pointless to try to encapsulate it, and Nichol Thomson, who does all the serial sectioning of C. elegans at the MRC with remarkable consistency, and ultimately without whom none of this work would have been possible. I would also like to thank the Medical Research Council for a Training Award, and Kings College for a Research Fellowship.
With the exception of the technical serial sectioning for the first part, this dissertation is the result of my own work and includes nothing which is the outcome of work done in collaboration. No part of this dissertation has been or is being submitted to any other University.