CAN
The Mind of 
	a Worm

Members: CANL, CANR.

CAN is a set of two cells that are closely associated with the excretory canal. The cell bodies of CAN are situated adjacent and dorsal to the excretory canal at about the level of the vulva (d). Anteriorly and posteriorly directed processes emanate from the cell bodies and run along the canal in close association with the processes of ALA and PVD. The anterior process of CAN ends just behind the nerve ring (d). The three canal-associated processes on each side, ALA, CAN and PVD, have not been completely reconstructed although they have been sampled in several places. Two of the processes end at about the level of the anus and the third enters the pre-anal ganglia and synapses onto PVC (ALA-d). A single synapse onto the lateral hypodermis has also been seen on one of the processes (c). Apart from a few rather unconvincing gap junctions to the excretory canal (b), no other synapses can be unambiguously assigned to CAN. Laser ablation experiments have, however, shown it to be essential for the survival of the animal (J. Sulston, unpublished observations) . Magnifications: (a) x 12750, (b, c) x 25500.


Web adaptation, Thomas Boulin, for Wormatlas, 2001, 2002