PHBL, PHBR

Type: Sensory neuron (chemosensory)
In MoW: PHB
Male Wiring Project:
PHBL, PHBR
In Wormbase: PHB, PHBL, PHBR
Lineage: AB plapppappp, AB prapppappp
Location: Right and left lumbar ganglia
Description: Phasmid neurons
Neurotransmitter/Neuropeptide:

- Glutamate
- Serotonin; low likelihood
- NLP-1; neuropeptide-like protein
(Pereira et al., 2015; Nathoo et al., 2001; Sawin et al., 2000; C. Loer, pers. comm.)
Innexin expression:
- INX-13
- INX-19 (NSY-5)
(Schumacher et al., 2012; Altun et al., 2009)


Receptor expression:
- OCR-2; TRPV channel proteins
- OSM-9; TRPV channel protein
- NPR-1 neuropeptide Y receptor like protein
- SRB-6; G protein-coupled serpentine receptor
(Coates and de Bono, 2002; Tobin et al., 2002; Colbert et al., 1997; Troemel et al., 1995)
Function:
- Modulate chemorepulsion behavior in worms (Hilliard et al., 2002)


Click image for closeup view Click pictures for higher resolution images


 
 

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PHBL (AB plapppappp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of PHBL (since last PHBL ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB plapppapp); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
PHBR (AB prapppappp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of PHBR (since last PHBR ancestor has not yet gone through its final division, the black sphere seen at the end of this movie is still AB prapppapp); dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).



Last revision: June 19, 2014
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