PHAL, PHAR

Type: Sensory neuron (chemosensory)
In MoW: PHA
Male Wiring Project:
PHAL, PHAR
In Wormbase: PHA, PHAL, PHAR
Lineage: AB plpppaapp, AB prpppaapp
Location: Right and left lumbar ganglia
Description: Phasmid neurons. Ciliated, exposed to outside environment
Neurotransmitter/Neuropeptide:
- Glutamate
- NLP-7; neuropeptide-like protein
- NLP-14 ; neuropeptide-like protein
(Pereira et al., 2015; Nathoo et al., 2001)
Innexin expression:
- INX-13
- INX-19 (NSY-5)
(Schumacher et al., 2012; Altun et al., 2009)


Receptor expression:
- GCY-12; guanylyl cyclase
- OCR-2; TRPV channel proteins
- OSM-9; TRPV channel protein
- NPR-1 neuropeptide Y receptor like protein
- PDFR-1; pigment dispersing factor (PDF-1) receptor
- SRG-13; G protein-coupled serpentine receptor
- SRB-6; G protein-coupled serpentine receptor
(Barrios et al, 2012; Coates and de Bono, 2002; Tobin et al., 2002; Colbert et al., 1997; Yu et al., 1997; Troemel et al., 1995)
Function:
- Modulate chemorepulsion behavior in worms (Hilliard et al., 2002)
- Part of the neuronal circuit that functions in mate-searching behavior of males (Barrios et al, 2012)


Click image for closeup view Click pictures for higher resolution images

 
 

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PHAL (AB plpppaapp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of PHAL; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).

 
 

Click here for larger version
PHAR (AB prpppaapp) development in the embryo.
Dorsal view. Bottom is left side of the embryo. Spheres indicate individual nuclei. Black sphere: ancestors of PHAR; dark grey spheres: apoptotic cells; other cells follow the WA color code (after they acquire specific cell or tissue identities). 0 min is fertilization. Click on the movie for higher resolution rendition (by A. Santella & Z. Bao).


Last revision: June 19, 2014
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