PVPL (called PVU in male), PVPR (called PVS in male)

Type: Interneuron
In MoW: PVP
Male Wiring Project:
PVU, PVS
In Wormbase: PVP, PVPL, PVPR
Lineage: AB plppppaaa, AB prppppaaa
Location: Pre-anal ganglion
Description: Interneuron. Differences in connectivity observed between hermaphrodites and males. In hermaphrodites PVP neurites were observed to make branches around the vulva suggesting they may form synapses with egg-laying muscles (WBG, 1999). The PVPL/PVPR processes cross over in the pre-anal ganglion and then grow forward on the opposite side of the cord to the nerve ring. The PVPL process invariably crosses in front of the PVPR process. PVPL and PVPR somas are nearly opposite one another in the embryo and early larval stages. However, in the adult, this symmetry and order is lost and cells are situated almost linearly within PAG (Durbin, 1987).
Neurotransmitter:
Function:
Along with PVQL, PVPR pioneers the left side ventral cord and this function appears to be a joint action of these two processes. When PVPR precursor is ablated in the embryo, PVQL and AVKR growth cones migrate towards the right side. (Durbin, 1987; Antebi et al., 1997).
Receptor Expression:





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For Male Wiring Project details see Emmons lab website.

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