AVEL, AVER

Type: Interneuron
In MoW: AVE
Male Wiring Project: AVEL, AVER
In Wormbase: AVE, AVEL, AVER
Lineage: AB alpppaaaa, AB praaaaaaa
Location: Lateral ganglia of head
Description: Ventral cord interneurons. AVE's have the same postsynaptic targets as AVD's, but processes of AVE's are restricted to anterior cord, ending shortly before vulva.
Neurotransmitter: FLP-1 precursor (Nelson et al., 1998).
Function: Command interneuron. Drive backward movement of the animal along with AVA, AVD and A-type motor neurons. See Locomotory circuit.
Receptor Expression: Express glutamate receptor subunits, GLR-1, GLR-2, GLR-5, NMR-1 and NMR-2 (Maricq et al., 1995; Brockie et al., 2001).

Click image for closeup view Click pictures for higher resolution images and to play movie

See Quicktime movie of confocal stack opt-3::GFP expression in AVEL, AVER (by Christina Gleason/Miller lab).

Fei et al. (2000) A novel H(+)-coupled oligopeptide transporter (OPT3) from Caenorhabditis elegans with a predominant function as a H(+) channel and an exclusive expression in neurons, J. Biol. Chem. 275: 9563-71. (Note that neurons shown as AVA's in this publication are actually AVE's. D. Miller, pers. comm.).

 
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