neuron pages.pvt

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CONNECTIVITY:

MOW

Male Wiring Project

Sulston et al., 1980

IN WB

CELL ID:

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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

PVT
Interneuron
ABplpappppa
Preanal ganglion
Unknown
None

DESCRIPTION

Interneuron, projects along ventral cord to ring. Hermaphrodites and males exhibit some differences in PVT connectivity.

Functions: Midline neuroblast, serves as a guidepost neuron to guide growing axons from the lumbar ganglia in the posteriormost region of the ventral cord. When PVT is ablated embryonically, these axons follow multiple routes to enter ventral cord instead of making tight bundles (A. Antebi et al, 1997) (Ren X-C. et al., 1999). Postembryonically, PVT functions to keep the ventral cord fascicles intact. Early larval ablation of PVT induces axons of AVKL/R, PVQL/R, HSNL/R and RMEV to aberrantly cross the ventral midline (Aurelio O. et al, 2002).

Receptor expression: Expresses a splice variant of the tyramine receptor SER-2 (variable expression) (Tsalik E. L. et al, 2003). Expresses the serotonin receptor SER-4 (variable expression) (Tsalik E. L. et al, 2003).

Male Wiring Project

For Male Wiring Project details see "Connectivity" link in Emmons lab website.

CELL	TYPE	LINEAGE	LOCATION	NEUROTRANSMITTER	ASSOCIATED GLIA
PVT	Interneuron	ABplpappppa	Preanal ganglion	Unknown	None
DESCRIPTION
Interneuron, projects along ventral cord to ring. Hermaphrodites and males exhibit some differences in PVT connectivity. Functions: Midline neuroblast, serves as a guidepost neuron to guide growing axons from the lumbar ganglia in the posteriormost region of the ventral cord. When PVT is ablated embryonically, these axons follow multiple routes to enter ventral cord instead of making tight bundles (A. Antebi et al, 1997) (Ren X-C. et al., 1999). Postembryonically, PVT functions to keep the ventral cord fascicles intact. Early larval ablation of PVT induces axons of AVKL/R, PVQL/R, HSNL/R and RMEV to aberrantly cross the ventral midline (Aurelio O. et al, 2002). Receptor expression: Expresses a splice variant of the tyramine receptor SER-2 (variable expression) (Tsalik E. L. et al, 2003). Expresses the serotonin receptor SER-4 (variable expression) (Tsalik E. L. et al, 2003).