neuron pages.dva

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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

DVA

Interneuron
AB.prppppapp Dorsorectal ganglion
Not known
None

DESCRIPTION

Ring interneurons.

Functions: Mechanosensory integration. The PVD and DVA neurons are presynaptic to both the forward and backing interneurons, and provide input to both the anterior and posterior touch circuits. Animals lacking these neurons respond to tap stimulus with diminished forward accelerations and reversals. These neurons, therefore, seem to maintain the overall activity of the touch circuit (Driscoll M., Kaplan J., 1997)( Wicks S. R. et al, 1996)

Receptor expression: Expresses glutamate receptor subunits, GLR-4, GLR-5 and NMR-1(Brockie P.J. et al 2001). Expresses a splice variant of the tyramine receptor SER-2 (Tsalik E. L. et al, 2003). Variably expresses the serotonin receptor SER-4 (can be instead DVC neuron) (Tsalik E. L. et al, 2003). Suggested to express GABA-A/glycine receptor-like protein GGR-3 (Fujiwara et al, 1996).

See glr-4-GFP expression in DVA (Brockie P.J. et al 2001).

CELL	TYPE	LINEAGE	LOCATION	NEUROTRANSMITTER	ASSOCIATED GLIA
DVA	Interneuron	AB.prppppapp	Dorsorectal ganglion	Not known	None
DESCRIPTION
Ring interneurons. Functions: Mechanosensory integration. The PVD and DVA neurons are presynaptic to both the forward and backing interneurons, and provide input to both the anterior and posterior touch circuits. Animals lacking these neurons respond to tap stimulus with diminished forward accelerations and reversals. These neurons, therefore, seem to maintain the overall activity of the touch circuit (Driscoll M., Kaplan J., 1997)( Wicks S. R. et al, 1996) Receptor expression: Expresses glutamate receptor subunits, GLR-4, GLR-5 and NMR-1(Brockie P.J. et al 2001). Expresses a splice variant of the tyramine receptor SER-2 (Tsalik E. L. et al, 2003). Variably expresses the serotonin receptor SER-4 (can be instead DVC neuron) (Tsalik E. L. et al, 2003). Suggested to express GABA-A/glycine receptor-like protein GGR-3 (Fujiwara et al, 1996).