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CELL TYPE LINEAGE LOCATION NEUROTRANSMITTER ASSOCIATED GLIA

AVBL
AVBR
Interneuron AB plpaapaap
AB prpaapaap Lateral ganglia of head
Not known
None

DESCRIPTION

One of four bilaterally symmetric interneuron pairs (AVA, AVB, AVD, and PVC) with large-diameter axons that run the entire length of the ventral nerve cord and provide input to the ventral cord motor neurons. Synapse onto B-type (VB, DB) and AS motor neurons. Formerly called beta.

Functions: Command interneuron. Functions as driver cell for forward locomotion. Drives forward movement of the animal along with the touch modulator, PVC, and B-type motor neurons. See Locomotory circuit.

Receptor expression: Express glutamate receptor subunits, GLR-1 and GLR-5 (Maricq A. V. et al 1995)(Brockie P.J. et al 2001). Express G protein-coupled serpentine receptor, SRA-11 (Troemel E. et al 1995). Suggested to express GABA-A/glycine receptor-like protein GGR-3 (Fujiwara et al, 1996). Express UNC-8, a DEG/ENaC family member homologous to subunits of a candidate mechanically gated ion channel (Tavernarakis N. et al, 1997).

CELL	TYPE	LINEAGE	LOCATION	NEUROTRANSMITTER	ASSOCIATED GLIA
AVBL AVBR	Interneuron	AB plpaapaap AB prpaapaap	Lateral ganglia of head	Not known	None
DESCRIPTION
One of four bilaterally symmetric interneuron pairs (AVA, AVB, AVD, and PVC) with large-diameter axons that run the entire length of the ventral nerve cord and provide input to the ventral cord motor neurons. Synapse onto B-type (VB, DB) and AS motor neurons. Formerly called beta. Functions: Command interneuron. Functions as driver cell for forward locomotion. Drives forward movement of the animal along with the touch modulator, PVC, and B-type motor neurons. See Locomotory circuit. Receptor expression: Express glutamate receptor subunits, GLR-1 and GLR-5 (Maricq A. V. et al 1995)(Brockie P.J. et al 2001). Express G protein-coupled serpentine receptor, SRA-11 (Troemel E. et al 1995). Suggested to express GABA-A/glycine receptor-like protein GGR-3 (Fujiwara et al, 1996). Express UNC-8, a DEG/ENaC family member homologous to subunits of a candidate mechanically gated ion channel (Tavernarakis N. et al, 1997).